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CRBN ligand-192

CRBN ligand-192 is an E3 ligand that can be used for the synthesis of PROTACs, such as PROTAC BRD4 Degrader-41. PROTAC BRD4 Degrader-41 is a potent BRD4 PROTAC degrader with anti-cancer activity[1].

Product Specifications

UNSPSC

12352005

Target

Ligands for E3 Ligase

Related Pathways

PROTAC

Field of Research

Cancer

Smiles

N[C@@H](CCC1=CC=CC=C1)C(NC2CCC(NC2=O)=O)=O

Molecular Formula

C15H19N3O3

Molecular Weight

289.33

References & Citations

[1]Huang K, et al. Design, synthesis, and biological evaluation of novel PROTACs based on unnatural dipeptide CRBN ligands. Eur J Med Chem. 2026 Feb 5;303:118387.

Shipping Conditions

Room temperature

Scientific Category

Reference compound1

Clinical Information

No Development Reported

Isoform

Cereblon

Frequently Asked Questions

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