CRBN ligand-192
CRBN ligand-192 is an E3 ligand that can be used for the synthesis of PROTACs, such as PROTAC BRD4 Degrader-41 (HY-179734) . PROTAC BRD4 Degrader-41 is a potent BRD4 PROTAC degrader with anti-cancer activity[1].
Product Specifications
UNSPSC
12352005
Target
Ligands for E3 Ligase
Related Pathways
PROTAC
Field of Research
Cancer
Smiles
N[C@@H](CCC1=CC=CC=C1)C(NC2CCC(NC2=O)=O)=O
Molecular Formula
C15H19N3O3
Molecular Weight
289.33
References & Citations
[1]Huang K, et al. Design, synthesis, and biological evaluation of novel PROTACs based on unnatural dipeptide CRBN ligands. Eur J Med Chem. 2026 Feb 5;303:118387.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Isoform
Cereblon
Curated Selection
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