CRBN ligand-191
CRBN ligand-191 is an E3 ligand that can be used for the synthesis of PROTACs, such as PROTAC ALK degrader-4 (HY-179732) [1].
Product Specifications
CAS Number
[1519514-63-6]
UNSPSC
12352005
Target
Ligands for E3 Ligase
Related Pathways
PROTAC
Field of Research
Cancer
Smiles
NC1(CCC1)C(NC2C(NC(CC2)=O)=O)=O
Molecular Formula
C10H15N3O3
Molecular Weight
225.24
References & Citations
[1]Huang K, et al. Design, synthesis, and biological evaluation of novel PROTACs based on unnatural dipeptide CRBN ligands. Eur J Med Chem. 2026 Feb 5;303:118387.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Isoform
Cereblon
Curated Selection
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