HPK1-IN-67
HPK1-IN-67, a HPK1 inhibitor, is a ligand for target protein for PROTAC. HPK1-IN-67 can be used for synthesis of PROTACs, such as PROTAC HPK1 Degrader-7 (HY-179727) [1].
Product Specifications
UNSPSC
12352005
Target
Ligands for Target Protein for PROTAC; MAP4K
Related Pathways
MAPK/ERK Pathway; PROTAC
Field of Research
Others
Smiles
O=C(O)C1=C(C)NC(/C=C2C(NC3=C\2C=C(C4=CN=C5OCCNC5=C4C)C=C3)=O)=C1C
Molecular Formula
C24H22N4O4
Molecular Weight
430.46
References & Citations
[1]Zhang Z, et al. Design, synthesis, and pharmacological evaluation of novel isoindoline-based HPK1 degraders. Eur J Med Chem. 2026 Jan 15;302 (Pt 3) :118366.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Isoform
MAP4K1/HPK1
Curated Selection
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