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HPK1-IN-67

HPK1-IN-67, a HPK1 inhibitor, is a ligand for target protein for PROTAC. HPK1-IN-67 can be used for synthesis of PROTACs, such as PROTAC HPK1 Degrader-7.

Product Specifications

UNSPSC

12352005

Target

Ligands for Target Protein for PROTAC; MAP4K

Related Pathways

MAPK/ERK Pathway; PROTAC

Field of Research

Others

Smiles

O=C(O)C1=C(C)NC(/C=C2C(NC3=C\2C=C(C4=CN=C5OCCNC5=C4C)C=C3)=O)=C1C

Molecular Formula

C24H22N4O4

Molecular Weight

430.46

References & Citations

[1]Zhang Z, et al. Design, synthesis, and pharmacological evaluation of novel isoindoline-based HPK1 degraders. Eur J Med Chem. 2026 Jan 15;302 (Pt 3) :118366.

Shipping Conditions

Room temperature

Scientific Category

Reference compound1

Clinical Information

No Development Reported

Isoform

MAP4K1/HPK1

Frequently Asked Questions

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