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CRBN ligand-190

CRBN ligand-190 is a is a CRBN-type E3 ubiquitin ligase ligand, can be used for the synthesis of PROTACs, such as PROTAC HPK1 Degrader-7.

Product Specifications

CAS Number

1543013-96-2

UNSPSC

12352005

Target

Ligands for E3 Ligase

Related Pathways

PROTAC

Field of Research

Inflammation/Immunology

Smiles

FC1=CC(N(C(N2)=O)CCC2=O)=CC=C1

Molecular Formula

C10H9FN2O2

Molecular Weight

208.19

References & Citations

[1]Zhang Z, et al. Design, synthesis, and pharmacological evaluation of novel isoindoline-based HPK1 degraders. Eur J Med Chem. 2026 Jan 15;302 (Pt 3) :118366.

Shipping Conditions

Room temperature

Scientific Category

Reference compound1

Clinical Information

No Development Reported

Isoform

Cereblon

Frequently Asked Questions

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