α-Glucosidase-IN-106
α-Glucosidase-IN-106 (Compound 17F) is an inhibitor of α-glucosidase with an IC50 of 14.9 μM. α-Glucosidase-IN-106 can effectively inhibit the peak of blood glucose after sucrose loading in normal mice, and shows a more significant anti-hyperglycemic effect in diabetic mice. α-Glucosidase-IN-106 can be used for research on diabetes[1].
Product Specifications
UNSPSC
12352005
Target
Glycosidase
Related Pathways
Metabolic Enzyme/Protease
Field of Research
Metabolic Disease
Smiles
O=C1C2=C(OC3=C1C(O)=CC(OCC4=CN([C@H]5[C@@H]([C@@H]6OC(C)(C)OC6)O[C@]7([H])OC(C)(C)O[C@@]75[H])N=N4)=C3)C=C(C=CC=C8)C8=C2
Molecular Formula
C32H31N3O9
Molecular Weight
601.60
References & Citations
[1]García-Mejía CD, et al. Triazole-containing xanthone-furanose/pyranose hybrids: synthesis of potential α-glucosidase inhibitors. Eur J Med Chem. 2026 Jan 15;302 (Pt 3) :118384.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Isoform
Glucosidase
Curated Selection
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