MTase-IN-2
MTase-IN-2 (compound 32) is a potent NS5 methyltransferase inhibitor with IC50s of 2.14 μM and 2.01 μM against the Dengue virus (DENV3) MTase domain and Zika virus (ZIKV) NS5 MTase domain, respectively[1].
Product Specifications
UNSPSC
12352005
Target
Dengue Virus
Related Pathways
Anti-infection
Field of Research
Infection
Smiles
O[C@H]1[C@@H](O)[C@H](N2C=NC3=C(N)N=CN=C23)O[C@@H]1CN(CC[C@H](N)C(O)=O)CC4=CN(CC5=CSC(N)=N5)N=N4
Molecular Formula
C21H28N12O5S
Molecular Weight
560.59
References & Citations
[1]Otava T, et al. Exploring advanced methodologies for NS5 methyltransferase targeted drug discovery. Eur J Med Chem. 2026 Feb 5;303:118388.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Curated Selection
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