Anti-MRSA agent 41
Anti-MRSA agent 41 (Compound 3d) is a prodrug of Mupirocin (HY-B0958), being a cholesterol disulfide conjugate of Mupirocin. Anti-MRSA agent 41 shows no antibacterial activity or cytotoxicity in vitro. Anti-MRSA agent 41 demonstrates strong anti-MRSA infection efficacy in systemic bacteremia and pneumonia mouse models. Anti-MRSA agent 41 can be used in antibiotic resistance research[1].
Product Specifications
UNSPSC
12352005
Target
Bacterial; Drug Intermediate
Related Pathways
Anti-infection; Others
Field of Research
Infection
Smiles
O[C@@H]1[C@@H](C[C@@H]2O[C@H]2[C@@H](C)[C@@H](O)C)CO[C@@H](C/C(C)=C/C(OCCCCCCCCC(OCCSSCCC(O[C@@H]3CC(CC[C@]4(C)[C@]5([H])CC[C@@]6(C)[C@@]4([H])CC[C@@H]6[C@H](C)CCCC(C)C)[C@]5(C)CC3)=O)=O)=O)[C@@H]1O
Molecular Formula
C59H100O11S2
Molecular Weight
1049.55
References & Citations
[1]Gong Z, et al. Design, synthesis, and evaluation of mupirocin prodrugs restoring systemic efficacy against MRSA. Eur J Med Chem. 2026 Feb 5;303:118406.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Curated Selection
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