JAK1/2 ligand 1
JAK1/2 ligand 1 is the ligand of JAK1/2 and can be used for the synthesis of PROTACs, such as JAK1/2 Ligand-Linker Conjugates 1 (HY-179716[1].
Product Specifications
CAS Number
[1026028-96-5]
UNSPSC
12352005
Target
JAK; Ligands for Target Protein for PROTAC
Related Pathways
Epigenetics; JAK/STAT Signaling; PROTAC; Protein Tyrosine Kinase/RTK; Stem Cell/Wnt
Field of Research
Inflammation/Immunology
Smiles
O=C(O)C1=CC=C(C2=NC(NC3=CC=CC=C3)=NC=C2)C=C1
Molecular Formula
C17H13N3O2
Molecular Weight
291.30
References & Citations
[1]Li G, et al. Development of potent JAK1/2 PROTAC degraders for the treatment of inflammatory bowel diseases. Eur J Med Chem. 2026 Jan 15;302 (Pt 3) :118374.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Isoform
JAK1; JAK2
Curated Selection
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