MOR agonist-5
MOR agonist-5 is a selective and potent mu-opioid receptor (MOR) agonist with an EC50 of 0.25 nM. MOR agonist-5 shows an EC50 of 10 nM for DOR and >10000 nM for KOR and NOR. MOR agonist-5 exerts significant antinociceptive activity. MOR agonist-5 can be used for the research of pain[1].
Product Specifications
CAS Number
3085132-31-3
UNSPSC
12352005
Target
Opioid Receptor
Related Pathways
GPCR/G Protein; Neuronal Signaling
Field of Research
Neurological Disease
Smiles
NC(C1=CC(N2[C@H]3CC[C@@H]2CN(CCCC4=CC=CC=C4)C3)=CC=C1)=O
Molecular Formula
C22H27N3O
Molecular Weight
349.47
References & Citations
[1]Trivedi RR, et al. N- (3-Hydroxyphenyl) -3,8-diazabicyclooctanes as opioid receptors probes. 1. Investigation of the phenolic hydroxyl group. Eur J Med Chem. 2025;298:117991.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Isoform
NOP Receptor/ORL1; δ Opioid Receptor/DOR; κ Opioid Receptor/KOR; μ Opioid Receptor/MOR
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