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Antifungal agent 141

Antifungal agent 141, a Phenoxazine (HY-34463) derivative, is an antifungal agent. Antifungal agent shows potent antifungal activity in Cryptococcus neoformans and Candida albicans with MIC values of 2 and 4 µg/mL. Antifungal agent 141 can be used for the research of cryptococcal meningitis[1].

Product Specifications

UNSPSC

12352005

Target

Drug Derivative; Fungal

Related Pathways

Anti-infection; Others

Field of Research

Infection

Smiles

CC1=CC=C2C(OC(C=C(C(F)(F)F)C=N3)=C3N2CC4=CC=C(CN5CCC(CCO)CC5)C=C4)=C1

Molecular Formula

C28H30F3N3O2

Molecular Weight

497.55

References & Citations

[1]Guin S, et al. Second generation repurposing of phenothiazine antipsychotic drugs as antifungal lead molecules via optimization of phenoxazine derivatives. Eur J Med Chem. 2026;302 (Pt 3) :118373.

Shipping Conditions

Room temperature

Scientific Category

Reference compound1

Clinical Information

No Development Reported

Curated Selection

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