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Procaspase-3 activator 1

Procaspase-3 activator 1 is a potent procaspase-3 activator. Procaspase-3 activator directly activates procaspase-3 through zinc chelation, thereby inducing apoptosis and inhibiting cancer cell proliferation. Procaspase-3 activator 1 can be used for the research of non-small cell lung cancer (NSCLC) and melanoma[1].

Product Specifications

UNSPSC

12352005

Target

Apoptosis; Caspase

Related Pathways

Apoptosis

Field of Research

Cancer

Smiles

CCCCCCOC1=C(C=C(C=C1)/C=N/NC(/C=C/C2=CC(O)=C(C=C2)O)=O)OC

Molecular Formula

C23H28N2O5

Molecular Weight

412.48

References & Citations

[1]Guo Z, et al. Cafeic acid benzylidene hydrazides as novel procaspase-3 activators: Rational design, synthesis, and mechanistic evaluation of antitumor efficacy. Bioorg Chem. 2025;166:109174.

Shipping Conditions

Room temperature

Scientific Category

Reference compound1

Clinical Information

No Development Reported

Isoform

Caspase 3

Curated Selection

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