JAK2-IN-18
JAK2-IN-18 (Compound example1) is a selective JAK2 inhibitor. JAK2-IN-18 can inhibit JAK-STAT signaling and shows an IC50 of [1].
Product Specifications
CAS Number
3108318-77-7
UNSPSC
12352005
Target
JAK; STAT
Related Pathways
Epigenetics; JAK/STAT Signaling; Protein Tyrosine Kinase/RTK; Stem Cell/Wnt
Field of Research
Cardiovascular Disease
Smiles
COC(C(NC1=CC(NC(C2CC2)=O)=NN3C1=NC=C3)=CC=C4)=C4C5=CC(C6(CC6)C7)=C(C=C5)C(N7CC8=CC=CC(C(N(C)C)=O)=N8)=O
Molecular Formula
C37H36N8O4
Molecular Weight
656.73
References & Citations
[1]Xiaowei Wu, et al. Jak2 inhibitors and their use as pharmaceuticals. WO2025240835A2. 2025-11-20
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Isoform
JAK2; STAT5
Frequently Asked Questions
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