STING agonist-49-PAB-Ala-Val-CO-C2-mal

STING agonist-49-PAB-Ala-Val-CO-C2-mal, a pep-cSTING linker-payload, is a drug-linker conjugate for ADC. STING agonist-49-PAB-Ala-Val-CO-C2-mal can be used for ADC synthesis[1].

Product Specifications

CAS Number

[2803608-03-7]

UNSPSC

12352005

Target

Drug-Linker Conjugates for ADC

Related Pathways

Antibody-drug Conjugate/ADC Related

Field of Research

Cancer

Smiles

O=C([C@H](C)NC([C@H](C(C)C)NC(CCN1C(C=CC1=O)=O)=O)=O)NC2=CC=C(COC(N(C)CCCOC3=CC(C(N)=O)=CC4=C3N(C(NC(C5=CC(C)=NN5CC)=O)=N4)C/C=C/CN6C(NC(C7=CC(C)=NN7CC)=O)=NC8=CC(C(N)=O)=CC(OC)=C86)=O)C=C2

Molecular Formula

C62H73N17O13

Molecular Weight

1264.35

References & Citations

[1]Gruber DR, et al. Targeted delivery of a potent STING agonist payload via an antibody drug conjugate drives robust antitumor activity in preclinical models. Mol Cancer Ther. 2025 Oct 29.