ST17
ST17 is a light-activatable ST13 prodrug. ST17 readily releases ST13 upon irradiation. ST13 is a selective, slow- and tight-binding HDAC1/HDAC2 inhibitor with antiproliferative activity. ST17 can be used in the research of melanoma and breast cancer[1].
Product Specifications
UNSPSC
12352005
Target
HDAC
Related Pathways
Cell Cycle/DNA Damage; Epigenetics
Applications
Cancer-programmed cell death
Field of Research
Cancer
Smiles
CC(NC1=CC=C(C(NC2=C(OCC3=CC(OC)=C(OC)C=C3[N+]([O-])=O)C=CC(C4=CC=CC=C4)=C2)=O)C=C1)=O
Molecular Formula
C30H27N3O7
Molecular Weight
541.55
References & Citations
[1]Honin I, et al. Ortho-Hydroxyanilides: Slow-Acting, Selective Histone Deacetylase 1/2 Inhibitors Suitable for Photocaging Applications. ACS Pharmacol Transl Sci. 2025 Nov 14;8 (12) :4385-4398.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Isoform
HDAC1; HDAC2
Curated Selection
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