ST17

ST17 is a light-activatable ST13 prodrug. ST17 readily releases ST13 upon irradiation. ST13 is a selective, slow- and tight-binding HDAC1/HDAC2 inhibitor with antiproliferative activity. ST17 can be used in the research of melanoma and breast cancer[1].

Product Specifications

UNSPSC

12352005

Target

HDAC

Related Pathways

Cell Cycle/DNA Damage; Epigenetics

Applications

Cancer-programmed cell death

Field of Research

Cancer

Smiles

CC(NC1=CC=C(C(NC2=C(OCC3=CC(OC)=C(OC)C=C3[N+]([O-])=O)C=CC(C4=CC=CC=C4)=C2)=O)C=C1)=O

Molecular Formula

C30H27N3O7

Molecular Weight

541.55

References & Citations

[1]Honin I, et al. Ortho-Hydroxyanilides: Slow-Acting, Selective Histone Deacetylase 1/2 Inhibitors Suitable for Photocaging Applications. ACS Pharmacol Transl Sci. 2025 Nov 14;8 (12) :4385-4398.