PDE4-IN-30
PDE4-IN-30 is a selective PDE4 inhibitor with an IC50 of 2.7 nM for PED4D2, targeting PDE4 through halogen bonding and metal coordination. PDE4-IN-30 exhibits at least 67-fold selectivity for other PDE subfamilies. PDE4-IN-30 can be used for the research of idiopathic pulmonary fibrosis[1].
Product Specifications
UNSPSC
12352005
Target
Phosphodiesterase (PDE)
Related Pathways
Metabolic Enzyme/Protease
Field of Research
Inflammation/Immunology
Smiles
NC1=C(C(NCCCC(NO)=O)=NC2=C(C=NN12)C3=CN(N=C3)C)Br
Molecular Formula
C14H17BrN8O2
Molecular Weight
409.24
References & Citations
A
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Isoform
PDE10; PDE4; PDE5; PDE8
Curated Selection
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