Antiviral agent 74
Antiviral agent 74 is an antiviral agent consisting of Cidofovir (HY-17438) prodrug and lipid chain. Antiviral agent 74 can inhibit the activity of viral DNA polymerase by transforming into Cidofovir.Antiviral agent 74 demonstrates potent antiviral activity against vacciniavirus (VACV) (EC50 = 0.156 μM) comparable to Brincidofovir (HY-14532) . Antiviral agent 74 shows superior potency against monkeypox virus (MPXV) with an EC50 vales of 0.202 μM. Antiviral agent 74 can be used for the research of virus infection[1].
Product Specifications
CAS Number
[3059641-72-1]
UNSPSC
12352005
Target
DNA/RNA Synthesis; Orthopoxvirus
Related Pathways
Anti-infection; Cell Cycle/DNA Damage
Applications
COVID-19-anti-virus
Field of Research
Infection
Smiles
OP(OCCS(CCCCCCCCCCCCCCCCCC)(=O)=O)(CO[C@H](CO)CN1C=CC(N)=NC1=O)=O
Molecular Formula
C28H54N3O8PS
Molecular Weight
623.78
References & Citations
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
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