STING agonist-49-CO-C2-mal-Cys
STING agonist-49-CO-C2-mal-Cys (compound 2), the derivative of STING agonist-49-CO-C2-mal (HY-179627), is the product of ADC catabolism and payload release, exhibits antitumor activity in vivo[1].
Product Specifications
CAS Number
[2803608-05-9]
UNSPSC
12352005
Target
Drug Derivative
Related Pathways
Others
Field of Research
Cancer
Smiles
O=C(C1=CC(C)=NN1CC)NC2=NC3=CC(C(N)=O)=CC(OC)=C3N2C/C=C/CN4C(NC(C5=CC(C)=NN5CC)=O)=NC6=C4C(OCCCN(C)C(CCN7C(CC(SC[C@@H](C(O)=O)N)C7=O)=O)=O)=CC(C(N)=O)=C6
Molecular Formula
C49H59N15O11S
Molecular Weight
1066.15
References & Citations
[1]Gruber DR, et al. Targeted delivery of a potent STING agonist payload via an antibody drug conjugate drives robust antitumor activity in preclinical models. Mol Cancer Ther. 2025 Oct 29.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Curated Selection
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