STING agonist-49

STING agonist-49 (Compound 1) is a STING agonist and can be used as a payload for ADCs. STING agonist-49 can be applied in lung cancer research[1].

Product Specifications

CAS Number

[2138299-66-6]

UNSPSC

12352005

Target

ADC Payload; STING

Related Pathways

Antibody-drug Conjugate/ADC Related; Immunology/Inflammation

Field of Research

Cancer

Smiles

O=C(C1=CC(C)=NN1CC)NC2=NC3=CC(C(N)=O)=CC(OC)=C3N2C/C=C/CN4C(NC(C5=CC(C)=NN5CC)=O)=NC6=C4C(OCCCNC)=CC(C(N)=O)=C6

Molecular Formula

C39H47N13O6

Molecular Weight

793.87

References & Citations

[1]Gruber DR, et al. Targeted delivery of a potent STING agonist payload via an antibody drug conjugate drives robust antitumor activity in preclinical models. Mol Cancer Ther. 2025 Oct 29.

Shipping Conditions

Room temperature

Scientific Category

Reference compound1

Clinical Information

No Development Reported

Curated Selection

Explore Other Products

Discover premium biology products from our extensive collection of 20M+ items

QH05077S 200 Tests

Human EIF2AK2 qPCR Primer Pair

Ask

View Details

NBP2-90712AF532 0.1 mL

Rabbit Monoclonal Carbonic Anhydrase X/CA10 Antibody (018) [Alexa Fluor 532]

Ask

View Details

313028 100 µL

DDB1 (DNA Damage-Binding Protein 1, DDB p127 Subunit, DNA Damage-Binding Protein a, DDBa, Damage-specific DNA-Binding Protein 1, HBV X-Associated Protein 1, XAP-1, UV-Damaged DNA-Binding Factor, UV-Damaged DNA-Binding Protein 1, UV-DDB 1, XPE-Binding Factor, XPE-BF, Xeroderma pigmentosum group E-Complementing Protein, XPCe, DDB1, XAP1)

Ask

View Details

20401051 1.0 mL

FCN1 Adenovirus (Human)

Ask

View Details

CHR2766 1000 / PCK

ScrewVial 9mm 0.35mL

Ask

View Details

NBP2-97609CL1 0.1 mL

Rabbit Polyclonal ERCC6L Antibody [CoraFluor 1]

Ask

View Details