Tyrosinase-IN-46

Tyrosinase-IN-46 (Compound III19) is a tyrosinase inhibitor. Its IC50 values for L-dopa and L-tyrosine are 3.24 and 2.79 nM respectively. Tyrosinase-IN-46 inhibits melanin synthesis and shows a significant anti-pigmentation effect. Tyrosinase-IN-46 can be used for the study of pigmentation disorders[1].

Product Specifications

UNSPSC

12352005

Target

Tyrosinase

Related Pathways

Metabolic Enzyme/Protease

Field of Research

Metabolic Disease

Smiles

CC1=CC=C(C=C1)/C=C/C(NCCCNC(/C=C/C2=CC=C(C=C2O)O)=O)=O

Molecular Formula

C22H24N2O4

Molecular Weight

380.44

References & Citations

[1]Wang J, et al. Discovery of Novel Dihydroxyphenol Tyrosinase Inhibitors for Treatment of Pigmentation: From Enzyme Screening to Three-Dimensional Human Skin Melanin Evaluation. J Med Chem. 2025 Nov 27;68 (22) :24047-24074.