Tyrosinase-IN-46
Tyrosinase-IN-46 (Compound III19) is a tyrosinase inhibitor. Its IC50 values for L-dopa and L-tyrosine are 3.24 and 2.79 nM respectively. Tyrosinase-IN-46 inhibits melanin synthesis and shows a significant anti-pigmentation effect. Tyrosinase-IN-46 can be used for the study of pigmentation disorders[1].
Product Specifications
UNSPSC
12352005
Target
Tyrosinase
Related Pathways
Metabolic Enzyme/Protease
Field of Research
Metabolic Disease
Smiles
CC1=CC=C(C=C1)/C=C/C(NCCCNC(/C=C/C2=CC=C(C=C2O)O)=O)=O
Molecular Formula
C22H24N2O4
Molecular Weight
380.44
References & Citations
[1]Wang J, et al. Discovery of Novel Dihydroxyphenol Tyrosinase Inhibitors for Treatment of Pigmentation: From Enzyme Screening to Three-Dimensional Human Skin Melanin Evaluation. J Med Chem. 2025 Nov 27;68 (22) :24047-24074.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Curated Selection
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