AT-9
AT-9 is an anthraquinone-triazene derivative. AT-9 exhibits strong DNA intercalation ability. AT-9 can also interact with Topo IIA. AT-9 exhibits anticancer activity against non-small cell lung cancer and cervical cancer[1].
Product Specifications
CAS Number
[3105449-36-0]
UNSPSC
12352005
Target
DNA Alkylator/Crosslinker; Drug Derivative; Topoisomerase
Related Pathways
Cell Cycle/DNA Damage; Others
Field of Research
Cancer
Smiles
O=C(C1=CC=C(C=C1)/N=N/N2CCOCC2)NC3=CC=CC4=C3C(C5=CC=CC=C5C4=O)=O
Molecular Formula
C25H20N4O4
Molecular Weight
440.45
References & Citations
[1]Jia ZH, et al. Discovery of anthraquinone-triazene derivatives as novel antitumor agents causing DNA damage. Bioorg Med Chem Lett. 2025 Dec 1;128:130347.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Isoform
Topo II
Curated Selection
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