Entadamide A-CO-C12
Entadamide A-CO-C12 is an Entadamide A derivative with potent anti-cancer activity, particularly against breast cancer cell lines. Entadamide A-CO-C12 promotes apoptosis, suppresses migratory ability, sphere formation, and stem-like cell populations. Entadamide A-CO-C12 inhibits tumor growth in a 4T1 mouse model. Entadamide A-CO-C12 can be used for the research of breast cancer[1].
Product Specifications
UNSPSC
12352211
Target
Apoptosis; Bcl-2 Family; Reactive Oxygen Species (ROS) ; Survivin
Related Pathways
Apoptosis; Immunology/Inflammation; Metabolic Enzyme/Protease; NF-κB
Field of Research
Cancer
Smiles
CCCCCCCCCCCCC(OCCNC(/C=C/SC)=O)=O
Molecular Formula
C19H35NO3S
Molecular Weight
357.55
References & Citations
[1]Bhulakshmi S, et al. Design and synthesis of Entadamide A derivatives targeting breast cancer: Insights into In silico, In vitro and In vivo models. Eur J Med Chem. 2026;302 (Pt 1) :118308.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Frequently Asked Questions
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