C201-0243
C201-0243 is a FcRn antagonist. C201-0243 exhibits antagonistic activity against IgG-FcRn binding with an IC50 of 3.439 nM. C201-0243 can be used in the research of IgG-mediated autoimmune diseases[1].
Product Specifications
CAS Number
931360-60-0
UNSPSC
12352005
Target
Fc Receptor (FcR)
Related Pathways
Immunology/Inflammation
Field of Research
Inflammation/Immunology
Smiles
O=C(C1=CC2=C(CO)C=NC(C)=C2OC1=N)NC3=CC(F)=CC=C3C
Molecular Formula
C18H16FN3O3
Molecular Weight
341.34
References & Citations
[1]Wu G, et al. Virtual Screening Combined with Phase Transition-FRET for Discovery of Small-Molecule FcRn Antagonists. Anal Chem. 2025 May 27;97 (20) :10661-10670.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Frequently Asked Questions
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