E3 Ligase Ligand-linker Conjugate 218

E3 Ligase Ligand-linker Conjugate 218 is an E3 ligase ligand-linker conjugate, and can be used for synthesis of PROTAC STAT6 degrader-2 (HY-179233) [1][2].

Product Specifications

CAS Number

[3067883-29-5]

UNSPSC

12352005

Target

E3 Ligase Ligand-Linker Conjugates

Related Pathways

PROTAC

Field of Research

Cancer

Smiles

O=C(O)CC1CCN(C2=C(N(C)C(N3C4C(NC(CC4)=O)=O)=O)C3=CC=C2)CC1

Molecular Formula

C20H24N4O5

Molecular Weight

400.43

References & Citations

[1]Stat6-selective degrader compound and use thereof. WO2025218706 A1. Gu, Peng, et al.|[2]Lu D, et al. Design, Optimization, and Development of RIPK1 Degraders with Improved Pharmacokinetic and Pharmacodynamic Properties. J Med Chem. 2025 Nov 13;68 (21) :22246-22263.