RWT9996
RWT9996 is a balanced GPR17 antagonist. RWT9996 has an inhibitory effect on G protein activation and β-arrestin-2 recruitment induced by MDL-29951. RWT9996 inhibits the phosphorylation of ERK/CREB and the accumulation of inositol phosphate (b IP1) induced by MDL-29951. RWT9996 can be used for the study of neurological diseases[1].
Product Specifications
CAS Number
[2877694-62-5]
UNSPSC
12352005
Target
Arrestin; Epigenetic Reader Domain; ERK; Transmembrane Glycoprotein
Related Pathways
Epigenetics; GPCR/G Protein; Immunology/Inflammation; MAPK/ERK Pathway; Stem Cell/Wnt
Field of Research
Neurological Disease
Smiles
FC1=C(NS(C2=CNC(C3=CC=CC=C3)=C2)(=O)=O)C=CC(C#N)=C1
Molecular Formula
C17H12FN3O2S
Molecular Weight
341.36
References & Citations
Shipping Conditions
Room temperature
Product MSDS
http://file.medchemexpress.com/batch_PDF/HY-179606/
Scientific Category
Reference compound1
Clinical Information
No Development Reported
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