SARM1-IN-8
SARM1-IN-8 (compound 6) is a competitive SARM1 base-exchange inhibitor. SARM1-IN-8 shows competitive inhibition of SARM1Δ1-27 activity with respect to the NAD+ substrate[1].
Product Specifications
UNSPSC
12352005
Target
Toll-like Receptor (TLR)
Related Pathways
Immunology/Inflammation
Field of Research
Neurological Disease
Smiles
NC1=NC=NC2=C1N=CN2[C@H]3[C@H](O)[C@H](O)[C@@H](COP(OP(OC[C@H]4[C@H](O)[C@H](O)[C@@H]([N+]5=CC=C(CC6=CC=C(NC(NC7=NC=CC=C7)=O)C=C6)C=C5)O4)([O-])=O)([O-])=O)O3.[NH4+].[NH4+].[Cl-]
Molecular Formula
C33H44ClN11O14P2
Molecular Weight
916.17
References & Citations
[1]Thomas Lundbäck, et al. The Rise and Fall of SARM1 Base-Exchange Inhibitors. bioRxiv. November 12, 2025.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Curated Selection
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