ERα ligand 3

ERα ligand 3 is a PROTAC target protein ligand that targets ERα. ERα ligand 3 can be used for the synthesis of CV2a (HY-179576) [1].

Product Specifications

UNSPSC

12352005

Target

Estrogen Receptor/ERR; Ligands for Target Protein for PROTAC

Related Pathways

PROTAC; Vitamin D Related/Nuclear Receptor

Field of Research

Others

Smiles

C[C@@]12/C=C3[C@](CC[C@]\3([H])COC)([H])[C@@H](C)[C@@H](O)[C@H](O[C@@H]4[C@H](O)[C@@H](O)[C@H](O)[C@@H](COC(C)(C)C=C)O4)C1=C(C(C)(CNC(C)=O)C)C[C@@H]2O

Molecular Formula

C35H57NO10

Molecular Weight

651.83

References & Citations

[1]Carlo J. A. Verhoef, et al. Induced ubiquitination of the partially disordered Estrogen Receptor alpha protein via a 14-3-3-directed molecular glue-based PROTAC design. bioRxiv. November 17, 2025.