GSK4394835A

GSK4394835A is a reversible covalent inhibitor of PDE3B with a pIC50 of 6.2. GSK4394835A can be used for cardiovascular disease research[1].

Product Specifications

CAS Number

[3032458-06-0]

UNSPSC

12352005

Target

Phosphodiesterase (PDE)

Related Pathways

Metabolic Enzyme/Protease

Field of Research

Cardiovascular Disease

Smiles

O=C(C1=CC(OC)=C2C=CC(OC)=CC2=N1)NC3=CC(C(N(CC4=CC=CC=C4)C)=O)=CC(B(O)O)=C3

Molecular Formula

C27H26BN3O6

Molecular Weight

499.32

References & Citations

[1]Samuel A. Eaton, et al. Covalent Binding of Boronic Acid-Based Inhibitor GSK4394835A to Phosphodiesterase 3B, a Drug Target for Cardiovascular Disease. bioRxiv. October 22, 2025.

Shipping Conditions

Room temperature

Scientific Category

Reference compound1

Clinical Information

No Development Reported

Isoform

PDE3

Curated Selection

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