JQ-1 (carboxylic acid) -amine-PEG8-cyanogen
JQ-1 (carboxylic acid) -amine-PEG8-cyanogen is a Target Protein Ligand-Linker Conjugate that incorporates a ligand for BRD4 (HY-78695) and a PROTAC linker, which recruits E3 ligases. JQ-1 (carboxylic acid) -amine-PEG8-cyanogen can be used for the synthesis of PROTAC BET Degrader-14 (HY-179588) [1].
Product Specifications
UNSPSC
12352005
Target
Epigenetic Reader Domain; Target Protein Ligand-Linker Conjugates
Related Pathways
Epigenetics; PROTAC
Field of Research
Cancer
Smiles
O=C(C[C@@H]1N=C(C2=CC=C(Cl)C=C2)C(C(C)=C(C)S3)=C3N4C1=NN=C4C)NCCOCCOCCOCCOCCOCCOCCOCCOCC#C
Molecular Formula
C38H52ClN5O9S
Molecular Weight
790.37
References & Citations
[1]Jacobsen IE, et al. Design of tissue-selective PROTACs through recruiting E3 ligase scaffolding protein MAGEA11. bioRxiv [Preprint]. 2025 Nov 3.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Isoform
BRD2; BRD3; BRD4
Explore Other Products
Discover premium biology products from our extensive collection of 20M+ items
CD1C (T-cell Surface Glycoprotein CD1c, CD1C) (MaxLight 650)
