Antileishmanial agent-38
Antileishmanial agent-38 (compound 197) is a host-directed small molecule antileishmanial agent exhibiting potent broad-spectrum activity against Leishmania spp. Antileishmanial agent-38 inhibits intracellular parasites primarily by targeting the host protein lysozyme, while also displaying direct activity against extracellular L. donovani promastigotes. Antileishmanial agent-38 can be used for leishmaniasis research[1].
Product Specifications
UNSPSC
12352005
Target
Parasite
Related Pathways
Anti-infection
Field of Research
Infection
Smiles
O=C(CNCC1=CC=CC(F)=C1)NC(C=C2)=CC=C2N3C(C(C=C4)=CC=C4C5=CC=C(C(F)(F)F)C=C5)=NC(C(F)(F)F)=C3
Molecular Formula
C32H23F7N4O
Molecular Weight
612.54
References & Citations
[1]Elizabeth G. Gurysh, et al. Discovery of Host-Directed Small Molecules with Broad Anti-Leishmanial Efficacy. bioRxiv. November 04, 2025.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Isoform
Leishmania
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