FSC (PEG4-αvβ6) ₃

FSC (PEG4-avb6) 3 is a tracer targeting αvβ6 integrin trimer (IC50 = 0.69 nM) . FSC (PEG4-avb6) 3 can be used for the study of head-and-neck, lung, breast, and pancreatic carcinomas[1].

Product Specifications

UNSPSC

12352005

Target

Integrin

Related Pathways

Cytoskeleton

Field of Research

Cancer

Smiles

O=C(N(O)CCCC(NC(CCOCCOCCOCCOCCN1N=NC(CCCCC(NCCCC[C@H](N(C)C([C@@H]2CCCN2C([C@H](CC3=CC=C(O)C=C3)NC([C@H](C)N4)=O)=O)=O)C(N[C@@H](CC5=CC=C(O)C=C5)C(N[C@@H](CCCNC(N)=N)C(NC(N[C@@H](CC(O)=O)C(N[C@@H](CC(C)C)C4=O)=O)=O)=O)=O)=O)=O)=C1)=O)C(OCC/C(C)=C\C6=O)=O)/C=C(C)\CCOC(C(NC(CCOCCOCCOCCOCCN7C=C(CCCCC(NCCCC[C@H](N(C)C([C@H]8N(C([C@H](CC9=CC=C(O)C=C9)NC([C@H](C)N%10)=O)=O)CCC8)=O)C(N[C@@H](CC%11=CC=C(O)C=C%11)C(N[C@@H](CCCNC(N)=N)C(NC(N[C@@H](CC(O)=O)C(N[C@@H](CC(C)C)C%10=O)=O)=O)=O)=O)=O)=O)N=N7)=O)CCCN(O)C(/C=C(CCOC(C(NC(CCOCCOCCOCCOCCN%12C=C(CCCCC(NCCCC[C@H](N(C)C([C@@H]%13CCCN%13C([C@H](CC%14=CC=C(O)C=C%14)NC([C@H](C)N%15)=O)=O)=O)C(N[C@@H](CC%16=CC=C(O)C=C%16)C(N[C@@H](CCCNC(N)=N)C(NC(N[C@@H](CC(O)=O)C(N[C@@H](CC(C)C)C%15=O)=O)=O)=O)=O)=O)=O)N=N%12)=O)CCCN6O)=O)/C)=O)=O

Molecular Formula

C237H354N54O69

Molecular Weight

5063.67

References & Citations

[1]Gariglio G, et al. Synthesis and Preclinical Development of a Novel 68Ga/89Zr-Labelled ανβ6-Integrin Targeting Trimer. bioRxiv [Preprint]. 2025 Nov 06:2025.11.05.686720.