Antiviral agent 73

Antiviral agent 73 (compound D13) is a potent intercellular movement inhibitor with antiviral activity. Antiviral agent 73 shows inactivation activity against potato virus Y (PVY) with an EC50 of 79.5 μg/mL. Antiviral agent 73 effectively inhibits virus infection by forming stable hydrogen bonds with Pro154 of PVY coat protein. Antiviral agent 73 can interfere with the process of Pro154-mediated viral intercellular trafficking in plasmodesmata. Antiviral agent 73 can be used for plant virus prevention and control[1].

Product Specifications

UNSPSC

12352005

Target

Others

Related Pathways

Others

Field of Research

Others

Smiles

COC1=CC=C(C=C1)/C=C2OC3=CC(OCC(NS(=O)(C4=CC=C(C=C4)Br)=O)=O)=CC=C3C\2=O

Molecular Formula

C24H18BrNO7S

Molecular Weight

544.37

References & Citations

[1]Dan Chen, et al. Sulfonamine-containing aurone derivatives act as inhibitors of intercellular movement of potato virus Y. iScience, Volume 28, Issue 12, 113914.