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ACS14

ACS14 is a derivative of Aspirin. ACS14 reduces Buthionine Sulfoximine (BSO) (HY-106376) -induced hypertension, plasma levels of thromboxane B2, 8-isoprostane, and insulin in rats, while GSH remained in the control range. ACS14 can be used for hypertension research[1].

Product Specifications

CAS Number

894430-68-3

UNSPSC

12352005

Target

Drug Derivative

Related Pathways

Others

Field of Research

Cardiovascular Disease

Purity

95.66

Solubility

DMSO : 50 mg/mL (ultrasonic)

Smiles

O=C(C1=C(OC(C)=O)C=CC=C1)OC2=CC=C(C(SS3)=CC3=S)C=C2

Molecular Formula

C18H12O4S3

Molecular Weight

388.48

References & Citations

[1]Rossoni G, et al. Activity of a new hydrogen sulfide-releasing aspirin (ACS14) on pathological cardiovascular alterations induced by glutathione depletion in rats. Eur J Pharmacol. 2010 Dec 1;648 (1-3) :139-45.

Shipping Conditions

Room Temperature

Storage Conditions

-20°C, 3 years; 4°C, 2 years (Powder)

Scientific Category

Reference compound1

Clinical Information

No Development Reported

Available Sizes

Frequently Asked Questions

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