CSH-4044

CSH-4044 can be isolated from fermented wheat germ extract. CSH-4044 is a unique benzothiazole compound. CSH-4044 can inhibit PIM3-driven BAD phosphorylation in pancreatic cancer cell lines as well as reducing DYRK1A-induced Tau phosphorylation in neuronal cells[1].

Product Specifications

UNSPSC

12352005

Target

Biochemical Assay Reagents; DYRK; Pim

Related Pathways

JAK/STAT Signaling; Others; Protein Tyrosine Kinase/RTK

Applications

Cancer-Kinase/protease

Field of Research

Cancer

Smiles

O=C(C1=CC(O)=C(OC)C=C1O)C2=NC3=CC(OC)=C(O)C=C3S2

Molecular Formula

C16H13NO6S

Molecular Weight

347.34

References & Citations

[1]Bencze, G., et al., (2025) . Identification and Validation of an inhibitor of the protein kinases PIM and DYRK. bioRxiv : the preprint server for biology, 2025.10.22.683941.