CSH-4044
CSH-4044 can be isolated from fermented wheat germ extract. CSH-4044 is a unique benzothiazole compound. CSH-4044 can inhibit PIM3-driven BAD phosphorylation in pancreatic cancer cell lines as well as reducing DYRK1A-induced Tau phosphorylation in neuronal cells[1].
Product Specifications
UNSPSC
12352005
Target
Biochemical Assay Reagents; DYRK; Pim
Related Pathways
JAK/STAT Signaling; Others; Protein Tyrosine Kinase/RTK
Applications
Cancer-Kinase/protease
Field of Research
Cancer
Smiles
O=C(C1=CC(O)=C(OC)C=C1O)C2=NC3=CC(OC)=C(O)C=C3S2
Molecular Formula
C16H13NO6S
Molecular Weight
347.34
References & Citations
[1]Bencze, G., et al., (2025) . Identification and Validation of an inhibitor of the protein kinases PIM and DYRK. bioRxiv : the preprint server for biology, 2025.10.22.683941.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Curated Selection
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