G13Ci-22
G13Ci-22 is a MRTX1133 (HY-134813) based KRAS G13C inhibitor. G13Ci-22 can be used for non-small cell lung cancer (NSCLC) research[1].
Product Specifications
UNSPSC
12352005
Target
Ras
Related Pathways
GPCR/G Protein; MAPK/ERK Pathway
Field of Research
Cancer
Smiles
O=C(C1=CC=CC(NC(C=C)=O)=C1)N2[C@@H]3CN(C4=C(C=NC(C5=CC(O)=CC6=C5C(C#C)=C(F)C=C6)=C7F)C7=NC(OC[C@@]89CCCN8C[C@H](F)C9)=N4)C[C@H]2CC3
Molecular Formula
C43H38F3N7O4
Molecular Weight
773.80
References & Citations
[1]Kirschner T, et al. Targeting KRASG13C with cyclic linker based inhibitors to explore warhead orientation. Sci Rep. 2025 Oct 31;15 (1) :38213.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Curated Selection
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