SOD1-aggregation-IN-1
SOD1-aggregation-IN-1 (compound 20) is a potent SOD aggregation inhibitor. SOD1-aggregation-IN-1 inhibits MG132 -induced mutant SOD1 intracellular aggregation in PC12-SOD1G85R YFP cells with an EC50 of 2.63 μM. SOD1-aggregation-IN-1 can be used for amyotrophic lateral sclerosis (ALS) research[1].
Product Specifications
UNSPSC
12352101
Target
SOD
Related Pathways
Immunology/Inflammation
Field of Research
Neurological Disease
Smiles
O=C1CC(CC(C(C)(OC2=CC(C(F)(F)F)=CC(C(F)(F)F)=C2)C)C1)=O
Molecular Formula
C17H16F6O3
Molecular Weight
382.30
References & Citations
[1]Elmansy MF, et al. Modifications of NU-9, a potent protein aggregation inhibitor. Properties and activity in a cellular model of amyotrophic lateral sclerosis. Bioorg Chem. 2025 Dec;167:109190.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
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