CA-II/TNAP-IN-1
CA-II/TNAP-IN-1 (compound 15) is a potent dual inhibitor against b-TNAP and b-CAII with IC50s of 0.69 and 1.25 μM, respectively. CA-II/TNAP-IN-1 exhibits anti-cancer effects. CA-II/TNAP-IN-1 can be used for cancer research[1].
Product Specifications
UNSPSC
12352005
Target
Carbonic Anhydrase; Phosphatase
Related Pathways
Metabolic Enzyme/Protease
Field of Research
Cancer
Smiles
O=C(NC(NCCC1=CNC2=C1C=CC=C2)=S)C3=CC=C(OC)C(OC)=C3
Molecular Formula
C20H21N3O3S
Molecular Weight
383.46
References & Citations
[1]Bibi M, et al. Computational and experimental investigations of novel 1,3-disubstituted thioureas as the dual inhibitor of b-TNAP and b-CAII enzyme for Cancer treatment. Bioorg Chem. 2025 Dec;167:109199.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Isoform
CA II
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