LIG48
LIG48 is ROS1 Kinase Domain and its mutant (G2032R ROS1 kinase domain) inhibitor. LIG48 remains within the mutated and wild-type ROS1 kinase domains. LIG48 can be used for the study of non-small cell lung cancer[1].
Product Specifications
UNSPSC
12352005
Target
ROS Kinase
Related Pathways
Protein Tyrosine Kinase/RTK
Field of Research
Cancer
Smiles
O=C(CN1C=CC(N)=NC1=O)N(C=C2C[C@@H](C(N3CCC[C@H]3C(N)=O)=O)N)C4=C2C=CC=C4
Molecular Formula
C22H25N7O4
Molecular Weight
451.48
References & Citations
[1]Maleki M, Fattahi A. In silico design of natural-based structures as drug candidates to inhibit ROS1 protein. Sci Rep. 2025 Nov 3;15 (1) :38346.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
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