CDK1-IN-8
CDK1-IN-8 is a CDK1 inhibitor. CDK1-IN-8 inhibits cell migration, induces apoptosis, and arrests the cell cycle at the G2/M phase. CDK1-IN-8 leads to a significant downregulation of CDK1 protein levels in HepG2 cells. CDK1-IN-8 can be used for the study of human hepatocellular carcinoma[1].
Product Specifications
CAS Number
3077717-99-5
UNSPSC
12352128
Target
Apoptosis; CDK
Related Pathways
Apoptosis; Cell Cycle/DNA Damage
Field of Research
Cancer
Smiles
OC1=C2C(C(C(C=C(C(NCCNC(C3=CC(F)=C(Cl)C=C3)P(OCC)(OCC)=O)=O)C=C4O)=C4C2=O)=O)=CC=C1
Molecular Formula
C28H27ClFN2O8P
Molecular Weight
604.95
References & Citations
[1]Li J, et al. Design, synthesis, and evaluation of phosphorylated rhein derivatives with enhanced antiproliferative activity. Bioorg Chem. 2025 Nov;166:109172.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Isoform
CDK1
Frequently Asked Questions
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