Umbelopsisin A
Umbelopsisin A is a GABAA and GABAB non-selective agonist. Umbelopsisin A activates the GABAergic pathway, including notch signaling and fatty acid metabolism. Umbelopsisin A shows dual neuroprotection against glutamate excitotoxicity in vitro (reducing ROS and cell death) and in vivo. Umbelopsisin A can be used for the study of glaucoma and broader neurodegenerative disease applications[1].
Product Specifications
UNSPSC
12352005
Target
GABA Receptor; Reactive Oxygen Species (ROS)
Related Pathways
Immunology/Inflammation; Membrane Transporter/Ion Channel; Metabolic Enzyme/Protease; Neuronal Signaling; NF-κB
Applications
Neuroscience-Neurodegeneration
Field of Research
Neurological Disease
Smiles
CC1=C(O)C(C)=C(C)C([C@@]2(C3=CNC4=CC=CC=C43)C(OC)=O)=C1OC2=O
Molecular Formula
C21H19NO5
Molecular Weight
365.38
References & Citations
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Frequently Asked Questions
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