FAK ligand-2-C6-amine
FAK ligand-2-C6-amine is a target protein ligand linker conjugate that contains a FAK ligand (HY-151010) and a PROTAC linker (HY-W011561), which can recruit E3 ligases. FAK ligand-2-C6-amine can be used for synthesis of BSJ-04-146 (HY-179512) [1].
Product Specifications
CAS Number
[2414478-60-5]
UNSPSC
12352005
Target
Target Protein Ligand-Linker Conjugates
Related Pathways
PROTAC
Field of Research
Cancer
Smiles
O=C(NC)C1=CC=CC=C1NC2=CC(NC3=CC(C)=C(C4CCN(CCCCCCN)CC4)C=C3OC(C)C)=NC=C2C(F)(F)F
Molecular Formula
C35H47F3N6O2
Molecular Weight
640.78
References & Citations
[1]Koide E, et al. Development and Characterization of Selective FAK Inhibitors and PROTACs with In Vivo Activity. Chembiochem. 2023 Oct 4;24 (19) :e202300141.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Curated Selection
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