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α-Glucosidase-IN-103

α-Glucosidase-IN-103 (compound 5u) is a potent and competitive α-Glucosidase inhibitor with an IC50 of 5.38 µM and a Ki of 3.57 µM. α-Glucosidase-IN-103 can be used for type 2 diabetes (T2DM) research[1].

Product Specifications

UNSPSC

12352005

Target

Glycosidase

Related Pathways

Metabolic Enzyme/Protease

Field of Research

Metabolic Disease

Smiles

O=S(N1C2=CC=CC=C2C(/C=N/NC(NC3=CC=C(Br)C=C3F)=S)=C1)(C4=CC=C(Cl)C=C4)=O

Molecular Formula

C22H15BrClFN4O2S2

Molecular Weight

565.87

References & Citations

[1]Naseer I, et al. Synthesis, in vitro, and in silico studies of 4-chlorophenyl-sulfonyl Indole based thiosemicarbazones as competitive α-glucosidase inhibitors. Sci Rep. 2025 Nov 6;15 (1) :38832.

Shipping Conditions

Room temperature

Scientific Category

Reference compound1

Clinical Information

No Development Reported

Isoform

Glucosidase

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