DHFR-IN-25
DHFR-IN-25 (Compound N2) is a type of inhibitor of dihydrofolate reductase (DHFR) . DHFR-IN-25 is a broad-spectrum and highly effective antibacterial agent, particularly showing significant effects on Candida albicans and Staphylococcus aureus. DHFR-IN-25 can be used for the study of local anti-infection[1].
Product Specifications
CAS Number
[3002069-20-4]
UNSPSC
12352005
Target
Bacterial; Dihydrofolate reductase (DHFR) ; Fungal
Related Pathways
Anti-infection; Metabolic Enzyme/Protease
Field of Research
Infection
Smiles
ClC1=CC(Cl)=C(C2=NC(C3=CC=CC=C3)=C(C4=CC=CC=C4)N2C5=CC=C(/N=N/C6=CC=CC=C6)C=C5)C=C1
Molecular Formula
C33H22Cl2N4
Molecular Weight
545.46
References & Citations
[1]Orujova NS, et al. In vitro, in silico, and DFT evaluation of antimicrobial imidazole derivatives with insights into mechanism of action. Sci Rep. 2025 Oct 28;15 (1) :37723.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Curated Selection
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