OTOP1-IN-1
OTOP1-IN-1 (compound C2.2) is a potent zebrafish Otopetrin 1 (OTOP1) inhibitor with an IC50 of 6.67 µM. OTOP1-IN-1 exhibits selectivity for zebrafish OTOP1 over mOTOP1 and hOTOP1[1].
Product Specifications
CAS Number
[2306539-75-1]
UNSPSC
12352005
Target
Others
Related Pathways
Others
Field of Research
Others
Smiles
C=C(C)COC1=C(NC(C2=C(C)NC=N2)=O)C=CC=C1
Molecular Formula
C15H17N3O2
Molecular Weight
271.31
References & Citations
[1]Burendei B, et al. Structure-guided discovery of Otopetrin 1 inhibitors reveals druggable binding sites at the intrasubunit interface. Nat Commun. 2025 Oct 23;16 (1) :9362.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Curated Selection
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