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Anticancer agent 285

Anticancer agent 285 is an orally active anticancer agent with highly effective and selective haspin-inhibiting IC50 = 18 nM) activity. Anticancer agent 285 can be used for the study of colorectal cancer[1].

Product Specifications

UNSPSC

12352005

Target

Haspin Kinase

Related Pathways

Cell Cycle/DNA Damage

Field of Research

Cancer

Smiles

O[C@@H]1[C@H](O)[C@@H](CN)S[C@H]1N(C2=C3C(N)=NC=N2)C=C3C#N

Molecular Formula

C12H14N6O2S

Molecular Weight

306.34

References & Citations

[1]Yum YA, et al. Design and development of 5'-modified 7-substituted 4'-thionucleosides as potent Haspin inhibitors: Synthesis and biological evaluation. Bioorg Chem. 2025 Nov;166:109146.

Shipping Conditions

Room temperature

Product MSDS

http://file.medchemexpress.com/batch_PDF/HY-179486/

Scientific Category

Reference compound1

Clinical Information

No Development Reported

CAS Number

[2878446-03-6]

Curated Selection

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