Anticancer agent 285
Anticancer agent 285 is an orally active anticancer agent with highly effective and selective haspin-inhibiting IC50 = 18 nM) activity. Anticancer agent 285 can be used for the study of colorectal cancer[1].
Product Specifications
CAS Number
[2878446-03-6]
UNSPSC
12352005
Target
Haspin Kinase
Related Pathways
Cell Cycle/DNA Damage
Field of Research
Cancer
Smiles
O[C@@H]1[C@H](O)[C@@H](CN)S[C@H]1N(C2=C3C(N)=NC=N2)C=C3C#N
Molecular Formula
C12H14N6O2S
Molecular Weight
306.34
References & Citations
[1]Yum YA, et al. Design and development of 5'-modified 7-substituted 4'-thionucleosides as potent Haspin inhibitors: Synthesis and biological evaluation. Bioorg Chem. 2025 Nov;166:109146.
Shipping Conditions
Room temperature
Product MSDS
http://file.medchemexpress.com/batch_PDF/HY-179486/
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Curated Selection
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