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CYP51-IN-31

CYP51-IN-31 (compound T24) is a selective CYP51 inhibitor with potent and broad-spectrum antifungal activity, including efficacy against drug-resistant fungal strains. CYP51-IN-31 exhibits fungicidal activity against Candida parapsilosis, anti-biofilm activity, and the ability to inhibit fungal morphological transitions. CYP51-IN-31 can be used for infection research[1].

Product Specifications

UNSPSC

12352005

Target

Cytochrome P450; Fungal

Related Pathways

Anti-infection; Metabolic Enzyme/Protease

Field of Research

Infection

Smiles

CN(CC(CN1C=NN=N1)(C2=CC=C(C=C2F)F)O)CC3=CC=C(C=C3)N4CCN(CC4)C5=CC=C(C=C5)OCC6=CC=C(C=C6)Cl

Molecular Formula

C35H36ClF2N7O2

Molecular Weight

660.16

References & Citations

[1]Zhang J, et al. Design, synthesis, and activity evaluation of novel tetrazole-based CYP51 inhibitors. Bioorg Chem. 2025 Nov;166:109132.

Shipping Conditions

Room temperature

Scientific Category

Reference compound1

Clinical Information

No Development Reported

Frequently Asked Questions

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