CYP51-IN-31
CYP51-IN-31 (compound T24) is a selective CYP51 inhibitor with potent and broad-spectrum antifungal activity, including efficacy against drug-resistant fungal strains. CYP51-IN-31 exhibits fungicidal activity against Candida parapsilosis, anti-biofilm activity, and the ability to inhibit fungal morphological transitions. CYP51-IN-31 can be used for infection research[1].
Product Specifications
UNSPSC
12352005
Target
Cytochrome P450; Fungal
Related Pathways
Anti-infection; Metabolic Enzyme/Protease
Field of Research
Infection
Smiles
CN(CC(CN1C=NN=N1)(C2=CC=C(C=C2F)F)O)CC3=CC=C(C=C3)N4CCN(CC4)C5=CC=C(C=C5)OCC6=CC=C(C=C6)Cl
Molecular Formula
C35H36ClF2N7O2
Molecular Weight
660.16
References & Citations
[1]Zhang J, et al. Design, synthesis, and activity evaluation of novel tetrazole-based CYP51 inhibitors. Bioorg Chem. 2025 Nov;166:109132.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
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